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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f1ea4efc551336ed62ce45e50a0ee4ab91218a346c4cfbcf8cfb51be0298d39' 
  AND token = 'smbwbgduLrZ6JGrO0j/33QGfbm5QaHEyaRslpf1uCL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}