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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f4ad0a00325703077547c9821ad2713af258eb4b06d7ed4b3516a17c44f0b1a' 
  AND token = 'dt0FfRCGNJN8lV0f1t4GEOJNTaqAAwMyC2ZrOHYGH44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}