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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca6111e9bd4f84c1eea51cfd0ad229eb5171074b2880f90ad579688b9d199022' 
  AND token = 'sUh+ic+cnDgs1Z+gTO/mUePY3xSWRK0EtpyFeq586yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}