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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6571b900254dc9b4571d698b6e8b05ce873828cec2309bd33263e8eb45f31ec5' 
  AND token = 'aw+m8rqmu8iiGsni4j/MswOxdE/LxxV/WV/RGwxDXgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}