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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8638efaa5b3c1b56c564b7c0dc90968c4c5535256144eab67713dd8a4c976359' 
  AND token = 'N8+9buRfsnohVIk0Zs/zDj1eMhz2E5VyX3EiqEGgQIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}