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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '192489664806a77771141812aed51cbfc2422407b9b81b3ef3c61e6e24524aab' 
  AND token = 'DVCoelJ78xZ7n2hr/hG4K+U0REScLYK5pUYamFdmZvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}