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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e799def1cba21f64f53bc28c3cb746fcfd9ef99a49d72c926954ca9429c3c2e' 
  AND token = 'SKn+JGXBs9lNy9P5cprcgGgixujtcGmL7UlvzkOUkIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}