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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866c9f78f464bb05060664cc9423438488ed65ec9105b4bbae043be77b7baec7' 
  AND token = 'b3nkOmx8z9jFi8AiXebwhsHj/3spvKMl8nvsNo1Xa/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}