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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab8eac579cfb375004c4a8a4031a1566cff3e3f68603792b74e032c0276e8c7f' 
  AND token = 'uxEEsyk4lW/+Bqre1MD8vT8A6l8yWMqTrSsJs6vI3yU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}