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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d229d6b1538f18752213aff339647bc5ffbb6ff8bd08082cf2901842cda7ef1' 
  AND token = '3wSwL0ZTCZj2YuGHNchl1PeuZSt5clY2EuJ7AiAhnfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}