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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c22c4e2e171c7d0ddab7f095e82b59f559f9887bdda2c97637928e0f1402cbd' 
  AND token = '8CI5PMNKLMtdCAMrcksLhUZzM6o6WAQaqGZTTj8Zb/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}