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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '308346405b2963301aab8f52d6f6ca7b21be33cdb6db36b8c34c5087a80756c1' 
  AND token = 'p352vd/D2ZnD2dfzNg6QooE+X0Ei2WYMKDIFh6TC+ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}