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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78bf5ae55ff29dc05b21ab4533bf61ec67d4fce2dedf45fd0785842d8ab286b2' 
  AND token = 'nIUSaBxQYykAcDu1IXcOG7dMq/XbczEEQZG2aqOC9VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}