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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e545d8af66c52dea55418e29a6b3e6887ef9804b6eb08b30e1c394889937ef2' 
  AND token = 'yI8XPMs54QWKQk2o+lioNT0KMkw3wu40ZMHsKiSUl7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}