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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c7ad4802351779e1c80ce03eb11b1fc96a4467408e60158d7c6993348eea614' 
  AND token = 'UVbYlZTOfDSGUr5Fd5yu7/yG1DHvEQxdlbsd8w7Wn8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}