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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c38e5b67ef5f945f2a9e1e62ce5e1b9479dae8ea8863d908fa005c274d71888' 
  AND token = 'Bso2y1fGN0xfJiXHq+a6mixaUlLU7s/z+VIyNBgV608=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}