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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7850348d1a8a6be1a76df9dabf1460f303d8094e2d71c5fa0ea1b420a49b64f' 
  AND token = 'rlpuydTsOf8otUUD6Dykc1v/7oYnWPTp148+9ZN3a5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}