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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa118b30ab0233de78a848deb2d5466be4fca55c8595f238eeec8f2822b5498' 
  AND token = 'jhnb0Y1j5Is/IaFHt1yZ5Qj4Ow5f33NUs5xYLhl+tIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}