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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b35f7ebce8b4d255cc241c6037d1f30223e7bd69da3f1550a0c2678ee68b7e' 
  AND token = 'qbCaWVKyIWp5ni+ePMDy5bgR21ReJjTyKCJcDM8mJ54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}