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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f3751e5c8a090ca2172444faccdaa3b903f3c5eb808d103c91b38c7800cc822' 
  AND token = 'JdA0NkWK9uZ2MEjXtOsoN2b2oSLauuJjGCfE2mlXRzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}