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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c58d2a53370d52d0ca1a5dfaa97bf1d0592bf04d13399405c7b169e9e8a8d98' 
  AND token = 'oZuTGPoD3SAU+oBbNT0xTdL95WNDhOTscRN3yMM2Bgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}