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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c82926c5a7acd305d936e94fde92acb8f461b2b97e5213dfca3e7b9e70e57b14' 
  AND token = 'dGyYwmY+XcZ9vkMEXi1VbUn93hzgsMFD5zgRpOpu3FE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}