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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b77479d8b10a38f9bf7c16e0654fc0bb4490a38385a387bb3e6647dfa435eee' 
  AND token = 'ES2K6y0+hasGrilI5HIcM0LM5J2mbkK+VjNQhTMpc00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}