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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78ee4e028cff79ad3a987b2714870d47699ef160ba918fd7d63f99f3d2212e9b' 
  AND token = 'jYa8wPRYaBrGSbyIM8O9m/PdIfBgJ6ZDmkRbJgtp5Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}