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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353403dcc6c8d618b467e0b5eda150b73c5c72b8a086cb2e5f8f46549cc326ad' 
  AND token = 'SeCkr/GRHBegA4TzDvXSlN2403vOn2g6kbKLFFoTNag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}