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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c3d47204c6e847e004f384e5d23162c082ce4e627b08292c6b4c58b4494a84' 
  AND token = 'VOs/P0CGsSZKTFWzPIR6CUpFO81czS6a7p7t8TCVQew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}