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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6acc0db43bb4b8110bb7b275a3b20dac651265fed5d9752bda1b934da2fc5c50' 
  AND token = 'OP2/I61a3PH/Q+mmH5cAt35UKxxhZaRmtuWdAsLQFfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}