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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d64b8a1da52a437845c79f8226d48109afb8c9ee760b22228498144a5f1954d' 
  AND token = 'WVSN6+Up1zn0C1Wscnv/onMfwPuRu18sSBNis/Ru8DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}