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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d4f6ce3f7ef972b5628806946b5c72c1be3ad5edab72877f70a0052ef7b1b3a' 
  AND token = 'pcTmeZLrh6g2FkEPzq32IX9a69lhUmj6xZYuH4CZLEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}