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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1530b3c50ac6195c120bb2c58586eda9bf56981bc92df64333b122a469f7d642' 
  AND token = 'rxsfPtInPDRtfXd3mWC7cudxUcCAyxGLtVnoTYRn6wA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}