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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f977c8505ade9cdcf8173ec3a80e6d45d2aa9beea73772541525229a93713dab' 
  AND token = 'NJoKQSv2lJOIyyXf4QhcTVxs+5YredsBIOL9Yt4h6Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}