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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80f688287d98eccdad4f0cfa44e455eeba0df33056c182f0f63adcf9c736763' 
  AND token = 'z+p80b+14camsxyi3WERdtPqgSlmws834BK8B9DGa6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}