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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e7d91bcb4633e3db5c6c5d6c28ba4a945cdcf3a757f171c66e08e0d2d3c1c3d' 
  AND token = 'ePGtfjxa/j8TYIPIJkdVXXpFMgLReHCL8EiU19Wt3Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}