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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ee859369c65f3f274d2b7414eb3468e8399db7378e260f190a58e5e243dde57' 
  AND token = 'SWvx50Itan060+NgMJEuBWfO8osBSHLjhrbWhERH2+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}