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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9af68bdf96112bc8eb3485244892e2a3e8a1053c1a35b27a10ab213c3421c5d6' 
  AND token = 'CwI+/GB0pBO7I1dWPkFWxXbEmDkgdqo4ISagv0cfmcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}