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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a59f09eb8c0e6e03000c7a02887699f0435281cd809923f007c9e98f5c57f9d' 
  AND token = 'T+3s4xpA6uOS1YkI956derro8a6mMD8lr6ATtd0KcRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}