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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a78ca18fb6062d026ef1ffc8573b526dd5b31ad635ce633072c8e1a9e9fac94d' 
  AND token = '4EUSG3mjJ7ASrvbvR0x8rdvwNJrX4WgpzG7V3zaBr60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}