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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0080633824feb8e522318f3625447081603791fc8d92d4d106fe5cc8150f077f' 
  AND token = 'E8Twpx1L2qQeRdwrvzYeWl2RtH6kRzeeOqr0zx69fGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}