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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5ec1ade5fbdfff95ccc1faafc611e7997ee542f4f9ecf02eb4ae4687052241' 
  AND token = 'KtG6pxX02C/dWhiRJ/IAvFtPJ01YU/Xg3Ho2T/GPY3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}