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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2491bd91e7d5b6a4dc089b4d9612f9b5e6fb535c1a315c6db3e4500968033006' 
  AND token = 'A/QQpoCsLuUYqg4q2xa+HcHa+wtaspfoM1wEEqnMaCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}