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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfea39302da0f27c663da1fd896420ffa2689e28e64c053c1eb890781b1adaa1' 
  AND token = 'ThCa9dOw+DCi2zytaUixmtdCc55vHvI6jNdH6cgUI+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}