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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27a7a41ce58dd176d91a3954f579f6c4539c1e35a13722b03f943564688875c9' 
  AND token = 'N6qKLmigKXW8dnVGeo/rGxkAtiP28Zps4gx7ZXDQ1Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}