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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aebcf5508bf2553190b24f7d07ac7e2cfe09abc5c72a1396479a1756395e1b61' 
  AND token = '4oZjiPV/hvr9Um7bcr1vtreR/KT31k/KGsTRAtdkDuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}