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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ee9e9b2601b0b22c8504746c5b307e1fd9ecbe543cbe28e903ca03dc2f9262' 
  AND token = 'URYUNDY2XwbVPdMN9N2VVE+j9vR35IWUbNPQ+GBEoHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}