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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a952acecc7ca73f0602b2bb69fadbb79e55ab7ab63289f1c622b1a8eb329b7b4' 
  AND token = 'u/n0UxN30Mhpo4p8Nv8P+rK6KEzQxLlEXZimVC74Jp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}