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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e52f7fbc320131c2361c927a5a5420defce063a6ee00a08086ab9825367982df' 
  AND token = 'wxdC5sprD+YzOnbKNz41EPAbqZvgsGBMW2OET9ur1m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}