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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0025a2aa422ddf193711fa4bc29bdf348a1bf79c8cde1147c12fd990dd5cd96f' 
  AND token = 'u/uVqmIt0Z2F3nyfxPfGsvedgtWFZPM7HwN5qVZkdIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}