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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec2a58365f55530e6d9ea64bfbd121533b6a4b5824faaeb7f75e449b8f0a20a' 
  AND token = 'hd7VxaZ+MRm8K5UBe/1K10A3mupf+pyvbUBeJR11Ggo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}