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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c189ed84bbc9d01a653ce99db391fd68459d1548cd56834d5fb6ecad196121' 
  AND token = 'VSBMJsLrHjFav6+kUnq5t61N2865yJq+ebiuAzOhsoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}