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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59135fa0720d6d955ab7e93aea704a67d9a4b3e60179ad38614838ac6291603' 
  AND token = 'S5yfb/c+Pdmd1gqQwy8VwCxx0rG2wH8zHLG3/5cERQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}